Arreaza stated that the White House decision to offer a reward for the capture of Maduro and other high-ranking officials for alleged drug trafficking and "narco-terrorism" prove the administration's "obsession" with Venezuela, and point to Trump's attempts to get better "electoral returns" in the state of Florida, RIA Novosti reported.
"The Bolivarian Republic of Venezuela denounces that at a time when humanity is facing the fiercest of pandemics, the government of Donald Trump is again attacking the people of Venezuela and its democratic institutions using a new form of coup d'etat, on the base of miserable, vulgar and unfounded accusations," the foreign minister added in a government statement.
In response to accusations that Venezuela is involved with leftist Colombian guerrilla group FARC to help export large shipments of cocaine into the United States and other countries, the foreign minister recalled Venezuela's role in peace negotiations between the Colombian government and the rebel organisation.
Arreaza accused the US of allowing the drug to be produced and shipped to North American under the oversight of its allied government in Colombia.
"The DEA has been the key international actor in the protection of drug production and processing in Colombia and the guarantor and vigilante of its transfer to the minds of young people in the United States," he noted.
The rare indictment from the US demonstrates a significant development by Washington in its ramping up of pressure against a sitting Venezuelan head of state. According to reports, Trump is increasingly frustrated with what he considers to be the lacklustre results of his Venezuela foreign policy.
The US has recognised the president of Venezuela's National Assembly, Juan Guaido, as the country's leader, although Guaido was not elected to the top office.
The United Nations, as well as UN Security Council member states China and Russia, continue to recognise the Maduro government.